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site is being upgraded home about us management thrust areas disclaimer dr boominathan’s quotes ideas bio-med ideas ideas for free bio-pharma/med ideas audience profile bio-medical ideas-7,900+ bio-med res grants aid p63 and p73 community how p63/p73/p53 field progresses noble laureate’s work tracked by gbmd ideas were viewed by world’s best 10 universities submit your ideas mirna therapeutics intellectual property development licensing opportunities partnerships investor opportunities educational tools scientific resources research research focus research themes research – ii dr boomi’s contributions (res) dr boomi’s caliber (sci) conference publications research publications research training ph.d/m.d/m.tech mentor what scientists saying peer/manuscript review press/media release conferences/meetings b-meriit introduction founder what we assure m.s program m.s in molecular cancer biology m.s in stem cell biology & regenerative medicine m.s in mol. medicine m.s in genome biology m.s in bio-medical sciences model building & model laboratory investor opportunities logo career guidance admission details registration terms and conditions career/opportunities contact us bio- medical/therapeutic ideas are the foundations of cure from a human disease bio- medical/therapeutic ideas are the foundations of cure from a human disease bio- medical/therapeutic ideas are the foundations of cure from a human disease check our recent posts total no of ideas: 10783 october 5, 2018 published by admin_auro at october 5, 2018 categories cancer ideas activating tumor suppressor gene network for cancer therapeutics: pioglitazone (trade name: actos), an anti-diabetic drug, increases the expression of tumor suppressors genes, such as rhob, p57kip2, p53, p53, tap63, tap73, ink4a/arf, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 5/october/2018, 11.36 pm from significance of the study to public health relevance: given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […] do you like it? 0 read more october 5, 2018 published by admin_auro at october 5, 2018 categories cancer cancer metastasis ideas awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: act1 (adaptor for il-17 receptors) increases the expression of tumor suppressors genes, such as btg2, timp3, p53, tap63, tap73, ink4a/arf, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 5/october/2018, 11.28 pm from significance of the study to public health relevance: given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […] do you like it? 0 read more october 5, 2018 published by admin_auro at october 5, 2018 categories diabetes ideas a probiotic way to treat tiidm and obesity-associated metabolic deficits: probiotic lactobaccilus gasseri sbt2055 increases lipocalin 2 (lcn2) expression, activates an mc4r-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to tiidm via down-regulation of its target gene, 5/october/2018, 11.01 pm introduction: what they say a study from the department of physiology-cellular biophysics, college of physicians and surgeons, columbia university, new york, new york, usa shows that “mc4r-dependent […] do you like it? 0 read more october 5, 2018 published by admin_auro at october 5, 2018 categories diabetes ideas a probiotic way to stay free of diabetes: probiotic lactobacillus gasseri-based therapy for body weight control, energy homeostasis and tiidm: probiotic lactobacillus gasseri inhibits dna methyltransferase 3a (dnmt3a) expression, increases fgf21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and tiidm, via up-regulation of its target gene, 5/september/2018, 10.46 pm introduction: what they say a study from nutritional sciences and toxicology department, university of california, berkeley, berkeley, united states shows that “dnmt3a is an epigenetic mediator […] do you like it? 0 read more october 5, 2018 published by admin_auro at october 5, 2018 categories ideas nafld a probiotic way to lower cholesterol, and triglycerides levels and to promote weight loss: repurposing the probiotic lactobacillus gasseri sbt 2055 (lg2055) into a cholesterol-lowering agent that inhibits non-alcoholic fatty liver disease (nafld): probiotic lactobacillus gasseri sbt 2055 (lg2055) decreases the levels of hmgcr, triglycerides, free cholesterol, and total cholesterol and prevents the progression of non-alcoholic fatty liver disease (nafld), via up-regulation of its target gene, 5/october/2018, 10.27 pm the significance of the study: given that: (1) 15-30% of western populations suffer from non-alcoholic fatty liver disease (nafld), while 6-25% of asian populations suffer from it; (2) 75 […] do you like it? 0 read more october 4, 2018 published by admin_auro at october 4, 2018 categories arthritis ideas molecular therapy for inflammation and arthritis: lidocaine (brand name: xylocaine and lignocaine), a drug used to treat numb tissue and ventricular tachycardia, increases il-9 levels, augments proliferation of ilc2s (type 2 innate lymphoid cells) and regulatory t (treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis, via up-regulation of its target genes, 4/october/2018, 6.41 pm introduction: what they say a study from department of internal medicine 3-rheumatology and immunology, friedrich alexander university erlangen-nürnberg (fau) and universitätsklinikum erlangen, erlangen, germany shows that […] do you like it? 0 read more october 4, 2018 published by admin_auro at october 4, 2018 categories ideas pain induction of the pd-1 pathway for pain therapy: nerve growth factor (ngf) increases the expression of pd-l1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 4/october/2018, 6.02 pm introduction:what they say: a recent study from institute of neurobiology, institutes of brain science and state key laboratory of medical neurobiology, collaborative innovation center for brain […] do you like it? 0 read more october 2, 2018 published by admin_auro at october 2, 2018 categories cancer cancer metastasis ideas awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: act1 (adaptor for il-17 receptors) increases the expression of tumor suppressors genes, such as anp32a, vhl, p53, p53, tap63, tap73, ink4a/arf, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 2/october/2018, 11.56 pm on the eve of mahatma gandhi birth anniversary we wish everyone a happy mahatma gandhi jayanti 2018. on this special occasion, we are happy to announce that ideas posted today (02/october/2018) will be […] do you like it? 0 read more october 2, 2018 published by admin_auro at october 2, 2018 categories autoimmune diabetes ideas molecular therapy for autoimmune diabetes (tidm): carbamazepine, an anticonvulsant drug used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy, and bipolar disorder, increases pd-l1 expression, increases tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses tidm, via up-regulation of its target gene, 2/october/2018, 11.48 pm on the eve of mahatma gandhi birth anniversary we wish everyone a happy mahatma gandhi jayanti 2018. on this special occasion, we are happy t